Analysis of Host Gene Expression Changes Reveals Distinct Roles for the Cytoplasmic Domain of the Epstein-Barr Virus Receptor/CD21 in B-Cell Maturation, Activation, and Initiation of Virus Infection

Epstein-Barr virus (EBV) attachment to human CD21 on the B-cell surface initiates infection. Whether CD21 is a simple tether or conveys vital information to the cell interior for production of host factors that promote infection of primary B cells is controversial, as the cytoplasmic fragment of CD2...

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Main Authors: Arredouani, Mohamed S., Bhasin, Manoj K., Sage, David R., Dunn, Laura K., Gill, Michael B., Agnani, Deep, Libermann, Towia A., Fingeroth, Joyce D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019091/
https://ncbi.nlm.nih.gov/pubmed/24600013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03099-13
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