Endoplasmic Reticulum Stress-Activated Transcription Factor ATF6α Requires the Disulfide Isomerase PDIA5 To Modulate Chemoresistance

ATF6α, a membrane-anchored transcription factor from the endoplasmic reticulum (ER) that modulates the cellular response to stress as an effector of the unfolded-protein response (UPR), is a key player in the development of tumors of different origin. ATF6α activation has been linked to oncogenic tr...

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Autors principals: Higa, Arisa, Taouji, Said, Lhomond, Stéphanie, Jensen, Devon, Fernandez-Zapico, Martin E., Simpson, Jeremy C., Pasquet, Jean-Max, Schekman, Randy, Chevet, Eric
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019026/
https://ncbi.nlm.nih.gov/pubmed/24636989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01484-13
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