A two-subunit type I DNA topoisomerase (reverse gyrase) from an extreme hyperthermophile.

A recently described reverse gyrase from the hyperthermophilic methanogen Methanopyrus kandleri is the only known example of a heterodimeric type I topoisomerase. The enzyme is made up of a 42-kDa subunit which covalently interacts with DNA (RgyA) and a 138-kDa subunit which binds ATP (RgyB). We hav...

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Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Krah, R, Kozyavkin, S A, Slesarev, A I, Gellert, M
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1996
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.106
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