A two-subunit type I DNA topoisomerase (reverse gyrase) from an extreme hyperthermophile.
A recently described reverse gyrase from the hyperthermophilic methanogen Methanopyrus kandleri is the only known example of a heterodimeric type I topoisomerase. The enzyme is made up of a 42-kDa subunit which covalently interacts with DNA (RgyA) and a 138-kDa subunit which binds ATP (RgyB). We hav...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1996
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.106 |
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