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Chemical Transformations That Yield Compounds with Distinct Activity Profiles

[Image: see text] We have systematically searched for chemical changes that generate compounds with distinct biological activity profiles. For this purpose, activity profiles were generated for ∼42000 compounds active against human targets. Unique activity profiles involving multiple target proteins...

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Detalhes bibliográficos
Main Authors: Hu, Ye, Bajorath, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018055/
https://ncbi.nlm.nih.gov/pubmed/24900343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2000609
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