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Clinical Outcome in Pediatric Glial and Embryonal Brain Tumors Correlates With In Vitro Multi-Passageable Neurosphere Formation

BACKGROUND: Cultured brain tumors can form neurospheres harboring tumorigenic cells with self renewal and differentiation capacities. Renewable neurosphere formation has clinical predictive value in adult malignant gliomas, yet its prognostic role for pediatric brain tumors is unknown. METHODS: Esta...

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Detalhes bibliográficos
Main Authors: Panosyan, Eduard H., Laks, Dan R., Masterman-Smith, Michael, Mottahedeh, Jack, Yong, William H., Cloughesy, Timothy F., Lazareff, Jorge A., Mischel, Paul S., Moore, Theodore B., Kornblum, Harley I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017922/
https://ncbi.nlm.nih.gov/pubmed/20589659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22627
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