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A chromatin structure‐based model accurately predicts DNA replication timing in human cells
The metazoan genome is replicated in precise cell lineage‐specific temporal order. However, the mechanism controlling this orchestrated process is poorly understood as no molecular mechanisms have been identified that actively regulate the firing sequence of genome replication. Here, we develop a me...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
European Molecular Biology Organization
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017678/ https://ncbi.nlm.nih.gov/pubmed/24682507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/msb.134859 |
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