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B7-H1 (PD-L1) is required for the development of multifunctional Th1 cells and immunity to primary, but not secondary Salmonella infection

Robust antibody and CD4 T cell responses are required for the resolution of Salmonella infection in susceptible mice. Here we examined the role of B7-H1 (PD-L1) in resistance to primary Salmonella infection. Infected B7-H1-deficient mice had significantly higher bacterial burdens at day 21 and day 3...

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Библиографические подробности
Главные авторы: Lee, Seung-Joo, O’Donnell, Hope, McSorley, Stephen J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017671/
https://ncbi.nlm.nih.gov/pubmed/20639491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000743
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