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B7-H1 (PD-L1) is required for the development of multifunctional Th1 cells and immunity to primary, but not secondary Salmonella infection
Robust antibody and CD4 T cell responses are required for the resolution of Salmonella infection in susceptible mice. Here we examined the role of B7-H1 (PD-L1) in resistance to primary Salmonella infection. Infected B7-H1-deficient mice had significantly higher bacterial burdens at day 21 and day 3...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017671/ https://ncbi.nlm.nih.gov/pubmed/20639491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000743 |
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