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Trypanosoma cruzi highjacks TrkC to enter cardiomyocytes and cardiac fibroblasts while exploiting TrkA for cardioprotection against oxidative stress

Chronic Chagas cardiomyopathy (CCC), caused by the obligate intracellular protozoan parasite Trypanosoma cruzi, is a major cause of morbidity and mortality in Latin America. CCC begins when T cruzi enters cardiac cells for intracellular multiplication and differentiation, a process that starts with...

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Bibliographic Details
Main Authors: Aridgides, Daniel, Salvador, Ryan, PereiraPerrin, Mercio
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017666/
https://ncbi.nlm.nih.gov/pubmed/23414299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12119
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