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Molecular Modeling of Lipid Membrane Curvature Induction by a Peptide: More than Simply Shape

Molecular dynamics simulations of an amphipathic helix embedded in a lipid bilayer indicate that it will induce substantial positive curvature (e.g., a tube of diameter 20 nm at 16% surface coverage). The induction is twice that of a continuum model prediction that only considers the shape of the in...

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Autors principals: Sodt, Alexander J., Pastor, Richard W.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017297/
https://ncbi.nlm.nih.gov/pubmed/24806928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.02.037
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