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Differential Effects of RGK Proteins on L-Type Channel Function in Adult Mouse Skeletal Muscle

Work in heterologous systems has revealed that members of the Rad, Rem, Rem2, Gem/Kir (RGK) family of small GTP-binding proteins profoundly inhibit L-type Ca(2+) channels via three mechanisms: 1), reduction of membrane expression; 2), immobilization of the voltage-sensors; and 3), reduction of P(o)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beqollari, D., Romberg, C.F., Meza, U., Papadopoulos, S., Bannister, R.A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017280/
https://ncbi.nlm.nih.gov/pubmed/24806927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.03.033
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