Rem uncouples excitation–contraction coupling in adult skeletal muscle fibers

In skeletal muscle, excitation–contraction (EC) coupling requires depolarization-induced conformational rearrangements in L-type Ca(2+) channel (Ca(V)1.1) to be communicated to the type 1 ryanodine-sensitive Ca(2+) release channel (RYR1) of the sarcoplasmic reticulum (SR) via transient protein–prote...

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Bibliographic Details
Published in:J Gen Physiol
Main Authors: Beqollari, Donald, Romberg, Christin F., Filipova, Dilyana, Meza, Ulises, Papadopoulos, Symeon, Bannister, Roger A.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485024/
https://ncbi.nlm.nih.gov/pubmed/26078055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411314
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