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Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis

BACKGROUND: Autophagy is a fundamental cell biological process whereby eukaryotic cells form membranes in the cytoplasm to sequester diverse intracellular targets. Although significant progress has been made in understanding the origins of autophagosomal organelles, the source of lipids that support...

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Autors principals: Dupont, Nicolas, Chauhan, Santosh, Arko-Mensah, John, Castillo, Eliseo F., Masedunskas, Andrius, Weigert, Roberto, Robenek, Horst, Proikas-Cezanne, Tassula, Deretic, Vojo
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016984/
https://ncbi.nlm.nih.gov/pubmed/24613307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.02.008
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