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Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy

Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as colitis and autoimmunity. Here, we show that the soluble excretory/secretory products of H. polygyrus (HES) potently suppress inflammation induced by allergens from the common...

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Autori principali: McSorley, H J, Blair, N F, Smith, K A, McKenzie, A N J, Maizels, R M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016792/
https://ncbi.nlm.nih.gov/pubmed/24496315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.123
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