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Genomic profiling of type-1 adult diabetic and aged normoglycemic mouse liver

BACKGROUND: Hyperglycemia induces chromatin remodeling with consequences on differential gene expression in mouse hepatocytes, similar to what occurs during aging. The liver is the central organ for the regulation of glucose homeostasis and xenobiotic and lipid metabolism and is affected by insulin...

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Bibliografische gegevens
Hoofdauteurs: Ghiraldini, Flávia G, Silveira, André B, Kleinjan, Dirk A, Gilbert, Nick, Mello, Maria Luiza S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016577/
https://ncbi.nlm.nih.gov/pubmed/24581510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6823-14-19
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