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Manipulation and potentiation of antimycobacterial immunity using recombinant bacille Calmette-Guérin strains that secrete cytokines.

Bacille Calmette-Guérin (BCG) is a live, attenuated strain of Mycobacterium bovis used widely for tuberculosis prophylaxis and bladder cancer immunotherapy, although it has limitations in both contexts. To investigate whether BCG's immunostimulatory properties could be modified, and to gain insight...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Murray, P J, Aldovini, A, Young, R A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40162/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8570663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.2.934
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