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Differential Polymer Structure Tunes Mechanism of Cellular Uptake and Transfection Routes of Poly(β-amino ester) Polyplexes in Human Breast Cancer Cells

Successful gene delivery with non-viral particles has several barriers, including cellular uptake, endosomal escape, and nuclear transport. Understanding the mechanisms behind these steps is critical to enhancing the effectiveness of gene delivery. Polyplexes formed with poly(β-amino ester)s (PBAEs)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, Jayoung, Sunshine, Joel C., Green, Jordan J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016154/
https://ncbi.nlm.nih.gov/pubmed/24320687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc4002322
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