A Stochastic Model Correctly Predicts Changes in Budding Yeast Cell Cycle Dynamics upon Periodic Expression of CLN2

In this study, we focus on a recent stochastic budding yeast cell cycle model. First, we estimate the model parameters using extensive data sets: phenotypes of 110 genetic strains, single cell statistics of wild type and cln3 strains. Optimization of stochastic model parameters is achieved by an aut...

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Bibliographic Details
Main Authors: Oguz, Cihan, Palmisano, Alida, Laomettachit, Teeraphan, Watson, Layne T., Baumann, William T., Tyson, John J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016136/
https://ncbi.nlm.nih.gov/pubmed/24816736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096726
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