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Inhibition of Autophagic Flux by Salinomycin Results in Anti-Cancer Effect in Hepatocellular Carcinoma Cells

Salinomycin raised hope to be effective in anti-cancer therapies due to its capability to overcome apoptosis-resistance in several types of cancer cells. Recently, its effectiveness against human hepatocellular carcinoma (HCC) cells both in vitro and in vivo was demonstrated. However, the mechanism...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Klose, Johannes, Stankov, Metodi V., Kleine, Moritz, Ramackers, Wolf, Panayotova-Dimitrova, Diana, Jäger, Mark D., Klempnauer, Jürgen, Winkler, Michael, Bektas, Hüseyin, Behrens, Georg M. N., Vondran, Florian W. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015957/
https://ncbi.nlm.nih.gov/pubmed/24816744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095970
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