A Depleting Anti-CD45 Monoclonal Antibody as Isolated Conditioning for Bone Marrow Transplantation in the Rat

OBJECTIVE: A monoclonal antibody (mAb) against the leukocyte common antigen CD45 (RT7 in rats) could facilitate bone marrow transplantation (BMT). This study in rats evaluates a depletive rat anti-RT7(a) mAb as isolated tool for BMT conditioning without using irradiation or any chemotherapeutic / im...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jäger, Mark D., Vondran, Florian W. R., Ramackers, Wolf, Röseler, Tilmann, Schlitt, Hans J., Bektas, Hüseyin, Klempnauer, Jürgen, Timrott, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854389/
https://ncbi.nlm.nih.gov/pubmed/27139494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154682
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