Pathogen Proliferation Governs the Magnitude but Compromises the Function of CD8 T Cells()

CD8(+) T cell memory is critical for protection against many intracellular pathogens. However, it is not clear how pathogen virulence influences the development and function of CD8(+) T cells. Salmonella typhimurium (ST) is an intracellular bacterium that causes rapid fatality in susceptible mice an...

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Bibliographic Details
Main Authors: Sad, Subash, Dudani, Renu, Gurnani, Komal, Russell, Marsha, van Faassen, Henk, Finlay, Brett, Krishnan, Lakshmi
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015947/
https://ncbi.nlm.nih.gov/pubmed/18424704
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