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Lack of Functional Selectin Ligand Interactions Compromises Long Term Tumor Protection by CD8(+) T Cells

Central memory CD8(+) T cells expressing the adhesion molecule CD62L (L-selectin) are potent mediators of anti-cancer immunity due to their ability to proliferate extensively upon antigen re-stimulation. The interaction of selectin with its ligands mediates leukocyte rolling along high endothelial v...

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Bibliografski detalji
Glavni autori: Stark, Felicity C., Gurnani, Komal, Sad, Subash, Krishnan, Lakshmi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281134/
https://ncbi.nlm.nih.gov/pubmed/22359671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032211
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