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Lack of Functional Selectin Ligand Interactions Compromises Long Term Tumor Protection by CD8(+) T Cells
Central memory CD8(+) T cells expressing the adhesion molecule CD62L (L-selectin) are potent mediators of anti-cancer immunity due to their ability to proliferate extensively upon antigen re-stimulation. The interaction of selectin with its ligands mediates leukocyte rolling along high endothelial v...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281134/ https://ncbi.nlm.nih.gov/pubmed/22359671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032211 |
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