The Chromatin “Landscape” of a Murine Adult β-Globin Gene Is Unaffected by Deletion of Either the Gene Promoter or a Downstream Enhancer

In mammals, the complex tissue- and developmental-specific expression of genes within the β-globin cluster is known to be subject to control by the gene promoters, by a locus control region (LCR) located upstream of the cluster, and by sequence elements located across the intergenic regions. Despite...

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Bibliographic Details
Main Authors: Cadiz-Rivera, Brenda, Fromm, George, de Vries, Christina, Fields, Jennifer, McGrath, Kathleen E., Fiering, Steven, Bulger, Michael
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015891/
https://ncbi.nlm.nih.gov/pubmed/24817273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092947
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