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An explorative analysis of ERCC1-19q13 copy number aberrations in a chemonaive stage III colorectal cancer cohort

BACKGROUND: Platinum-based chemotherapy has long been used in the treatment of a variety of cancers and functions by inducing DNA damage. ERCC1 and ERCC4 are involved in the removal of this damage and have previously been implicated in resistance to platinum compounds. The aim of the current investi...

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Hlavní autoři: Smith, David Hersi, Christensen, Ib Jarle, Jensen, Niels Frank, Markussen, Bo, Müller, Sven, Nielsen, Hans Jørgen, Brünner, Nils, Nielsen, Kirsten Vang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015772/
https://ncbi.nlm.nih.gov/pubmed/24144331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-489
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