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The role of CXC-chemokine receptor CXCR2 and suppressor of cytokine signaling-3 (SOCS-3) in renal cell carcinoma

BACKGROUND: Chemokine receptor signaling pathways are implicated in the pathobiology of renal cell carcinoma (RCC). However, the clinical relevance of CXCR2 receptor, mediating the effects of all angiogenic chemokines, remains unclear. SOCS (suppressor of cytokine signaling)-3 is a negative regulato...

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Main Authors: Stofas, Anastasios, Levidou, Georgia, Piperi, Christina, Adamopoulos, Christos, Dalagiorgou, Georgia, Bamias, Aristotelis, Karadimou, Alexandra, Lainakis, George A, Papadoukakis, Stefanos, Stravodimos, Konstantinos, Dimopoulos, Meletios-Athanasios, Patsouris, Efstratios, Gakiopoulou, Hariklia, Korkolopoulou, Penelope
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015755/
https://ncbi.nlm.nih.gov/pubmed/24593195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-149
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