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Methylglyoxal modulates endothelial nitric oxide synthase-associated functions in EA.hy926 endothelial cells

BACKGROUND: Increased levels of the sugar metabolite methylglyoxal (MG) in vivo were shown to participate in the pathophysiology of vascular complications in diabetes. Alterations of endothelial nitric oxide synthase (eNOS) activity by hypophosphorylation of the enzyme and enhanced monomerization ar...

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Detalhes bibliográficos
Main Authors: Su, Yang, Qadri, Syed M, Wu, Lingyun, Liu, Lixin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015749/
https://ncbi.nlm.nih.gov/pubmed/24050620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-12-134
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