Methylglyoxal modulates endothelial nitric oxide synthase-associated functions in EA.hy926 endothelial cells

BACKGROUND: Increased levels of the sugar metabolite methylglyoxal (MG) in vivo were shown to participate in the pathophysiology of vascular complications in diabetes. Alterations of endothelial nitric oxide synthase (eNOS) activity by hypophosphorylation of the enzyme and enhanced monomerization ar...

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Bibliographic Details
Main Authors: Su, Yang, Qadri, Syed M, Wu, Lingyun, Liu, Lixin
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015749/
https://ncbi.nlm.nih.gov/pubmed/24050620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-12-134
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