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Methylglyoxal modulates endothelial nitric oxide synthase-associated functions in EA.hy926 endothelial cells
BACKGROUND: Increased levels of the sugar metabolite methylglyoxal (MG) in vivo were shown to participate in the pathophysiology of vascular complications in diabetes. Alterations of endothelial nitric oxide synthase (eNOS) activity by hypophosphorylation of the enzyme and enhanced monomerization ar...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015749/ https://ncbi.nlm.nih.gov/pubmed/24050620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-12-134 |
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