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Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions.

DNA elements termed scaffold-associated regions (SARs) are AT-rich stretches of several hundred base pairs which are known to bind specifically to nuclear or metaphase scaffolds and are proposed to specify the base of chromatin loops. SARs contain sequences homologous to the DNA topoisomerase II cle...

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Detalhes bibliográficos
Main Authors: Adachi, Y, Käs, E, Laemmli, U K
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC401574/
https://ncbi.nlm.nih.gov/pubmed/2556260
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