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Haematopoietic stem cells require a highly regulated protein synthesis rate

Many aspects of cellular physiology remain unstudied in somatic stem cells. For example, there are almost no data on protein synthesis in any somatic stem cell. We found that the amount of protein synthesized per hour in haematopoietic stem cells (HSCs) in vivo was lower than in most other haematopo...

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Autors principals: Signer, Robert A.J., Magee, Jeffrey A., Salic, Adrian, Morrison, Sean J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015626/
https://ncbi.nlm.nih.gov/pubmed/24670665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13035
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