Immunopurification of adenomatous polyposis coli (APC) proteins

BACKGROUND: The adenomatous polyposis coli (APC) tumour suppressor gene encodes a 2843 residue (310 kDa) protein. APC is a multifunctional protein involved in the regulation of β-catenin/Wnt signalling, cytoskeletal dynamics and cell adhesion. APC mutations occur in most colorectal cancers and typic...

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Autors principals: Elliott, Kerryn L, Catimel, Bruno, Church, Nicole L, Coates, Janine L, Burgess, Antony W, Layton, Meredith J, Faux, Maree C
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015550/
https://ncbi.nlm.nih.gov/pubmed/24156781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-429
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