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Polyol pathway and diabetic nephropathy revisited: Early tubular cell changes and glomerulopathy in diabetic mice overexpressing human aldose reductase

Aims/Introduction:  The polyol pathway has long been involved in the pathogenesis of diabetic nephropathy. It remains still unclear, however, how the polyol pathway is implicated in this process. We explored the effects of the enhanced polyol pathway on renocortical tubular cells and glomeruli in ex...

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Detalhes bibliográficos
Main Authors: Hashimoto, Yasuhiro, Yamagishi, Shin‐Ichiro, Mizukami, Hiroki, Yabe‐Nishimura, Chihiro, Lim, Sun Woo, Kwon, H Moo, Yagihashi, Soroku
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015536/
https://ncbi.nlm.nih.gov/pubmed/24843470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2040-1124.2010.00071.x
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