Amelioration of Acute Kidney Injury in Lipopolysaccharide-Induced Systemic Inflammatory Response Syndrome by an Aldose Reductase Inhibitor, Fidarestat

BACKGROUND: Systemic inflammatory response syndrome is a fatal disease because of multiple organ failure. Acute kidney injury is a serious complication of systemic inflammatory response syndrome and its genesis is still unclear posing a difficulty for an effective treatment. Aldose reductase (AR) in...

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Autores principales: Takahashi, Kazunori, Mizukami, Hiroki, Kamata, Kosuke, Inaba, Wataru, Kato, Noriaki, Hibi, Chihiro, Yagihashi, Soroku
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257265/
https://ncbi.nlm.nih.gov/pubmed/22253906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030134
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