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High-Dose Interferon-γ Promotes Abortion in Mice by Suppressing Treg and Th17 Polarization

As a classic type I cytokine, interferon-gamma (IFN-γ) is known to manifest a miscarriage-inducing effect, although the specific mechanism is still unclear. To determine whether immune cells such as regulatory T (Treg) and Th17 cells are involved in these abortions, syngeneically pregnant (BALB/c×BA...

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Detalhes bibliográficos
Main Authors: Liu, Hai-Yan, Liu, Zhen-Kun, Chao, Huhe, Li, Zhongyin, Song, Zhihui, Yang, Ying, Peng, Jing-Pian
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015477/
https://ncbi.nlm.nih.gov/pubmed/24359574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2013.0062
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