A Randomized Controlled Trial of the Tumor Necrosis Factor-alpha Antagonist Infliximab in Treatment Resistant Depression: Role of Baseline Inflammatory Biomarkers

CONTEXT: Increased inflammatory biomarkers predict antidepressant non-response, and inflammatory cytokines can sabotage and circumvent mechanisms of action of conventional antidepressant therapy. OBJECTIVE: To determine whether inhibition of the inflammatory cytokine tumor necrosis factor (TNF)-alph...

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Hauptverfasser: Raison, Charles L., Rutherford, Robin E., Woolwine, Bobbi J., Shuo, Chen, Schettler, Pamela, Drake, Daniel F., Haroon, Ebrahim, Miller, Andrew H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015348/
https://ncbi.nlm.nih.gov/pubmed/22945416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/2013.jamapsychiatry.4
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