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Identification of CHRNA5 rare variants in African-American heavy smokers
The common CHRNA5 mis-sense coding single nucleotide polymorphism (SNP) rs16969968:G>A (D398N) has been shown repeatedly to confer risk for heavy smoking in individuals who carry the ‘A’ allele (encoding the 398N amino acid). The mis-sense SNP has a minor allele frequency (MAF) of ~40% in Europea...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015337/ https://ncbi.nlm.nih.gov/pubmed/24682045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YPG.0000000000000029 |
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