Intracisternal delivery of AAV9 results in oligodendrocyte and motor neuron transduction in the whole central nervous system of cats

Systemic and intracerebrospinal fluid delivery of adeno-associated virus serotype 9 (AAV9) has been shown to achieve widespread gene delivery to the central nervous system (CNS). However, after systemic injection, the neurotropism of the vector has been reported to vary according to age at injection...

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Detalhes bibliográficos
Main Authors: Bucher, T, Dubreil, L, Colle, M-A, Maquigneau, M, Deniaud, J, Ledevin, M, Moullier, P, Joussemet, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015314/
https://ncbi.nlm.nih.gov/pubmed/24572783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.16
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