Retrograde Gene Delivery to Hypoglossal Motoneurons Using Adeno-Associated Virus Serotype 9

Retrograde viral transport (i.e., muscle to motoneuron) enables targeted gene delivery to specific motor pools. Recombinant adeno-associated virus serotype 9 (AAV9) robustly infects motoneurons, but the retrograde transport capabilities of AAV9 have not been systematically evaluated. Accordingly, we...

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Autori principali: ElMallah, Mai K., Falk, Darin J., Lane, Michael A., Conlon, Thomas J., Lee, Kun-Ze, Shafi, Nadeem I., Reier, Paul J., Byrne, Barry J., Fuller, David D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015220/
https://ncbi.nlm.nih.gov/pubmed/22693957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2012.009
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