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Statistical hypothesis testing of factor loading in principal component analysis and its application to metabolite set enrichment analysis
BACKGROUND: Principal component analysis (PCA) has been widely used to visualize high-dimensional metabolomic data in a two- or three-dimensional subspace. In metabolomics, some metabolites (e.g., the top 10 metabolites) have been subjectively selected when using factor loading in PCA, and biologica...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015128/ https://ncbi.nlm.nih.gov/pubmed/24555693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-51 |
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