Disruption Of MYC-MiRNA-EZH2 Loop To Suppress Aggressive B-Cell Lymphoma Survival And Clonogenicity

c-MYC (hereafter MYC) overexpression has been recognized in aggressive B-cell lymphomas and linked to adverse prognosis. MYC activation results in widespread repression of miRNA expression and associated lymphoma aggressive progression. Our recent study identified a MYC-miRNAs-EZH2 feed-forward loop...

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Hlavní autoři: Zhao, Xiaohong, Lwin, Tint, Zhang, Xinwei, Huang, Andy, Wang, Jian, Marquez, Victor E., Chen-Kiang, Selina, Dalton, William S., Sotomayor, Eduardo, Tao, Jianguo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015113/
https://ncbi.nlm.nih.gov/pubmed/23538750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.94
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