Comparison of Different Suicide-Gene Strategies for the Safety Improvement of Genetically Manipulated T Cells

Use of adoptive T-cell therapy (ACT) is increasing; however, T-cell therapy can result in severe toxicity. Consequently, several suicide-gene strategies that allow selective destruction of the infused T cells have been described. We compared effectiveness of four such strategies in vitro in Epstein...

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Detalhes bibliográficos
Main Authors: Marin, Virna, Cribioli, Elisabetta, Philip, Brian, Tettamanti, Sarah, Pizzitola, Irene, Biondi, Andrea, Biagi, Ettore, Pule, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015080/
https://ncbi.nlm.nih.gov/pubmed/23186165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2012.050
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