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A Novel Hybrid Adenoretroviral Vector with More Extensive E3 Deletion Extends Transgene Expression in Submandibular Glands

Salivary glands are an attractive target for gene transfer. Salivary epithelial cells are considered to be highly differentiated and have low rates of cell division (∼6 months), affording the opportunity to obtain relatively long-term transgene expression in the absence of genomic integration. Here,...

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Detalhes bibliográficos
Main Authors: Zheng, Changyu, Cotrim, Ana P., Nikolov, Nikolay, Mineshiba, Fumi, Swaim, William, Baum, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015066/
https://ncbi.nlm.nih.gov/pubmed/22817829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2011.175
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