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Prevention of Radiation-Induced Oral Mucositis after Adenoviral Vector – Mediated Transfer of the Keratinocyte Growth Factor cDNA to Mouse Submandibular Glands

PURPOSE: The study aims to evaluate if human keratinocyte growth factor (hKGF), secreted after transduction of murine salivary glands with adenoviral vectors, can prevent oral mucositis resulting from radiation. EXPERIMENTAL DESIGN: Two serotype 5 adenoviral vectors encoding hKGF were constructed: A...

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Bibliografiske detaljer
Main Authors: Zheng, Changyu, Cotrim, Ana P., Sunshine, Abraham N., Sugito, Takayuki, Liu, Lina, Sowers, Anastasia, Mitchell, James B., Baum, Bruce J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769927/
https://ncbi.nlm.nih.gov/pubmed/19584147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0819
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