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Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1(-/-) mice
BACKGROUND: Airway inflammation and airway remodeling are the key contributors to airway hyperresponsiveness (AHR), a characteristic feature of asthma. Both processes are regulated by Transforming Growth Factor (TGF)-β. Caveolin 1 (Cav1) is a membrane bound protein that binds to a variety of recepto...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015038/ https://ncbi.nlm.nih.gov/pubmed/24138138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-110 |
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