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Effect of long‐term treatment with a small‐molecule glucokinase activator on glucose metabolism, lipid profiles and hepatic function
We investigated the long‐term effect of a glucokinase (GK) activator (GKA) on the changes in hepatic gene expression, glucose metabolism, lipid profiles and hepatic function in wild‐type mice and the haploinsufficiency of β‐cell‐specific GK mice on a high‐fat (HF) diet. Twenty weeks of GKA treatment...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014967/ https://ncbi.nlm.nih.gov/pubmed/24843498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2040-1124.2011.00104.x |
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