All-Trans Retinoic Acid and Sodium Butyrate Enhance Natriuretic Peptide Receptor A Gene Transcription: Role of Histone Modification

The objective of the present study was to delineate the mechanisms of GC-A/natriuretic peptide receptor-A (GC-A/NPRA) gene (Npr1) expression in vivo. We used all-trans retinoic acid (ATRA) and histone deacetylase (HDAC) inhibitor, sodium butyrate (NaBu) to examine the expression and function of Npr1...

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Detalhes bibliográficos
Main Authors: Kumar, Prerna, Periyasamy, Ramu, Das, Subhankar, Neerukonda, Smitha, Mani, Indra, Pandey, Kailash N.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014667/
https://ncbi.nlm.nih.gov/pubmed/24714214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.092221
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