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Genetic disruption of guanylyl cyclase/natriuretic peptide receptor-A upregulates renal (pro)renin receptor expression in Npr1 null mutant mice

The objective of the present study was to determifigne whether targeted-disruption of Npr1 gene (encoding for guanylyl cyclase/natriuretic peptide receptor-A; GC-A/NPRA) upregulates pro(renin) receptor (P)RR expression and leads to the activation of MAPKs in Npr1 gene-knockout mice. The Npr1 homozyg...

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Publicado en:Peptides
Main Authors: Periyasamy, Ramu, Das, Subhankar, Pandey, Kailash N.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821518/
https://ncbi.nlm.nih.gov/pubmed/30965084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2019.03.001
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