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An immunoglobulin mutator that targets G.C base pairs.

Hypermutation can be defined as an enhancement of the spontaneous mutation rate which the organism uses in certain types of differentiated cells where a high mutation rate is advantageous. At the immunoglobulin loci this process increases the mutation rate > 10(5)-fold over the normal, spontaneous r...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bachl, J, Wabl, M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40146/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8570647/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.2.851
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