An immunoglobulin mutator that targets G.C base pairs.
Hypermutation can be defined as an enhancement of the spontaneous mutation rate which the organism uses in certain types of differentiated cells where a high mutation rate is advantageous. At the immunoglobulin loci this process increases the mutation rate > 10(5)-fold over the normal, spontaneous r...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1996
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8570647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.2.851 |
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