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Facultative polypeptide translocation allows a single mRNA to encode the secreted and cytosolic forms of plasminogen activators inhibitor 2.

Two forms of plasminogen activators inhibitor 2 (PAI-2) are synthesized by human and murine monocytes/macrophages: one accumulates in the cytosol, while the other is translocated into the endoplasmic reticulum, glycosylated and secreted. We show here that a single mRNA encodes both forms of PAI-2. F...

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Publicat a:EMBO J
Autors principals: Belin, D, Wohlwend, A, Schleuning, W D, Kruithof, E K, Vassalli, J D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401459/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2583099/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08489.x
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